Abdel Abdellaoui
@dr_appie · Amsterdam, The Netherlands · joined 22 Jul 2015
Complex Trait Genetics | Population Genetics | Evolutionary Genetics | @AmsterdamUMC | @UvA_Amsterdam
10 003Followers
2 090Following
3 925Posts total
355.2KViews on collected posts
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Please do screen my thesis, it's a good read. Here it is in its entirety: https://t.co/cnA7RhxebQ
7.2K views · 81 likes
· 6 reposts · 0 replies
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@idevisch Hopelijk is professor Abdelaoui zijn doctoraatsscriptie goed gescreend op plagiaat voor hij zijn benoeming kreeg. Just saying.
7.7K views · 5 likes
· 0 reposts · 2 replies
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Thanks @Lotte_Lambrecht for the interview in the Belgian @destandaard. We discuss the complex relationship between DNA, behavior, and society, racist pseudoscience from people like @nathancofnas & @KirkegaardEmil, and polygenic embryo selection.
English: https://t.co/KMu6XTw9Dn
40.4K views · 100 likes
· 11 reposts · 20 replies
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@dr_appie @Nature Depois não reclamem quando algum maluco em 2080 utilize “Abdellaoui, 2026”, abrindo a sua tese para justificar limpeza genética no mundo. https://t.co/XvpELdHpyB
752 views · 4 likes
· 0 reposts · 0 replies
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@dr_appie @Nature Congratulations on this truly remarkable study
962 views · 2 likes
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Our genetic association study of the Big Five personality traits (extraversion, agreeableness, conscientiousness, neuroticism and openness to experience) came out in @Nature today, check it out here (open access): https://t.co/fOGnEWDWD7 https://t.co/sCmsrE2HTO
48K views · 576 likes
· 140 reposts · 11 replies
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How do nature, nurture, and their interplay drive inequality? 🧬🧠💰
New PhD position in social science genetics at @amsterdamumc and @VUamsterdam. Your supervisors will be: Titus Galama, Aysu Okbay, and me.
Apply by 21 July: https://t.co/GTDFQy8Yc3
Please share!
1.5K views · 14 likes
· 3 reposts · 0 replies
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@dr_appie @NatureHumBehav DNA and class are cosmic dice.
We dance in the shadows of our genetic lottery.
254 views · 3 likes
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Thank you to all co-authors! ❤️
@hilsomartin, @MartinKolk, @AdamRutherford, @mmuthukrishna, @fctropf, @melindacmills, Brendan Zietsch, Karin Verweij and Peter Visscher.
And many thanks to reviewer @SashaGusevPosts, the anonymous reviewers, and editor @libertyruth! 🙏🏽 https://t.
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SES is a social construct, influenced by heritable components—and leaving genetic traces behind.
Society doesn’t just shape opportunity—it shapes the patterns in our DNA.
Our full piece is here: https://t.co/Q5wAbt2B46
2.8K views · 24 likes
· 5 reposts · 1 replies
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Understanding these dynamics can help us explore societal structures of the past through genomes, reveal causes of present inequalities, and anticipate how inequalities might evolve with future social changes.
1.6K views · 12 likes
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Our research isn't a call for genetic intervention, but for a deeper understanding of how social structures shape both social and genetic outcomes, potentially creating reinforcing feedback loops that impact inequality.
1.6K views · 15 likes
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Social structures and genetics form a complex feedback loop that varies across time and cultures. Societies influence which traits are advantageous, while genetic distributions respond to these pressures, potentially reinforcing or reshaping social structures over generations.
1.7K views · 13 likes
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Natural selection works eventually through reproduction. Historically, there was a positive relationship between wealth and fertility. After the Industrial Revolution, this flipped. In several high-income countries, it's now shifting back.
3.2K views · 17 likes
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Assortative mating (partners resembling each other) also impacts genetic variation. Education shows the highest genetic assortative mating levels among traits studied so far, further concentrating certain genetic variants and resources within families, increasing inequality.
1.7K views · 14 likes
· 1 reposts · 1 replies
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This sorting impacts not just education but also regional differences in health outcomes, including COVID-19 vulnerability. Mortality rates from diseases and pandemics were always higher in lower SES regions. This hints at SES acting as a natural selection pressure. https://t.co/
2K views · 14 likes
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These patterns are partly driven by migration. Individuals with higher polygenic scores tend to move to more prosperous regions. This makes living circumstances of poor vs rich regions entangled with genetic effects, making it hard to separate genetic from environmental effects.
2.1K views · 31 likes
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Geographic analyses show that polygenic scores for educational attainment cluster regionally: lower scores cluster in economically disadvantaged regions, higher scores in more prosperous ones. Traits more genetically correlated with education show larger regional differences. htt
2.4K views · 23 likes
· 3 reposts · 1 replies
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Social processes like assortative mating, indirect effects, and gene–environment correlations make polygenic scores appear more predictive. These aren’t measurement errors, but real social dynamics that influence genetic associations without being direct genetic causes of SES. ht
2.5K views · 27 likes
· 4 reposts · 1 replies
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Genomics also shows SES to have heritable components. Polygenic scores explain ~12–16% of educational differences. However, subtle ancestry differences (population stratification) and selective participation (more healthy, educated and European ancestry subjects) distort results.
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· 1 reposts · 1 replies
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Heritability is a relative measure, as shown by interesting patterns in twin studies: In more equal societies, where opportunities are more equal, education’s heritability tends to rise. Among European women, it rose from 5% (1900–09) to 58% (1980–89). https://t.co/43tIh8hFB8
3.2K views · 36 likes
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Research on SES and genetics has a turbulent history. Galton’s 19th-century work led to the eugenics movement and its destructive legacy. That history still affects how SES and genetics are discussed today—often with tension between scientific curiosity and social responsibility.
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We begin with a historical overview of SES itself. Most hunter-gatherers were relatively egalitarian. With the Neolithic shift ~12,000 years ago, societies grew larger and more stratified—SES began shaping lives, and over time, potentially genomes. https://t.co/MVCNJcvMtF
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This thread summarizes our key findings, but Twitter's format necessitates some simplification and jargon. For a more comprehensive and nuanced understanding of this complex topic, I encourage reading the full paper, which we've written to be accessible to a wider audience.
3.5K views · 23 likes
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In every civilization, people end up sorted into levels of socio-economic status (SES). We explore the history, present, and future of scientific research on the complicated relationship between SES and DNA in @NatureHumBehav 💰🧬🎓
Link: https://t.co/Q5wAbt2B46
Thread below 👇🏽 ht
206.9K views · 575 likes
· 164 reposts · 15 replies
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Face aux comptes de taille comparable
8 posts des 90 derniers jours, à côté de la tranche de 10K–100K abonnés. diffusé largement, mais peu de ces spectateurs réagissent.
Vues médianes4 382ce compte954médiane pour 10K–100K
Portée, %43.80%ce compte3.32%médiane pour 10K–100K
Engagement, %0.43%ce compte1.87%médiane pour 10K–100K
| Indicateur | Ce compte | Médiane pour 10K–100K | Rapport |
|---|---|---|---|
| Vues médianes par post | 4 382 | 954 | 4.59× |
| Portée (vues ÷ abonnés) | 43.80% | 3.32% | 13.2× |
| Taux d'engagement | 0.43% | 1.87% | 0.23× |
Autres comptes de cette tranche → Comparer avec un autre compte → Comment ces repères sont établis →
Growth & engagement
How the posts we collected actually performed: views and reaction rate post by post, what the audience did with them, and where the follower count goes.
Views per post
1.7K26 Mar
1.6K
1.6K
2.8K
2.1K
25411 Jul
1.5K14 Jul
48K2 Sep
1K3 Sep
962
752
40.4K5 Sep
7.7K
7.2K6 Sep
Last 14 collected posts, oldest on the left. The scale is logarithmic: one post can outrun the rest a hundred times over.
Engagement rate per post
0.84%26 Mar
1.05%
0.82%
1.09%
1.07%
1.18%11 Jul
1.12%14 Jul
1.52%2 Sep
0.29%3 Sep
0.21%
0.53%
0.32%5 Sep
0.09%
1.20%6 Sep
Reactions — likes, reposts, replies and quotes — divided by views. Median for 10K–100K accounts is 1.87%.
What the audience does
Likes56.2%1 686 in total
Reposts11.6%349 in total
Replies2.2%65 in total
Bookmarks30.0%898 in total
Share of every reaction we collected for this account. Replies mean argument, reposts mean endorsement, bookmarks mean the post was worth keeping.
The follower curve appears once this account has two daily snapshots — we take one a day, and this one is on its first.
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