Fred Hutch Cancer Center

@fredhutch · Seattle · joined 08 Oct 2008

Making life beyond cancer a reality.

38 309Followers

3 388Following

36 097Posts total

3.9KViews on collected posts

Derniers posts

Fred Hutch Cancer Center@fredhutch4 Sep

🔬 Fred Hutch Cancer Center is hiring an Assistant or Associate Professor in the Basic Sciences Division @HutchBasicSci. Join a world-class research community in Seattle and help advance discoveries in fundamental biology. Apply: https://t.co/hACiOj2z8E https://t.co/3hvJHr2kj7 371 views · 7 likes · 2 reposts · 0 replies Open on X →

Fred Hutch Cancer Center@fredhutch4 Sep

Fred Hutch is at #PAXWest this weekend! Stop by our Stream for Fred Hutch booth in the Arch Building skybridge lobby to learn how you can harness the power of your community to save lives and make breakthrough discoveries in cancer and infectious disease. https://t.co/2coZ1Vfc4Y 359 views · 1 likes · 0 reposts · 0 replies Open on X →

Fred Hutch Cancer Center@fredhutch4 Sep

Fred Hutch and @seattlechildren's pediatric cancer survivorship expert Dr. Kavita Dhodapkar will study how immune aging from childhood cancer treatments may contribute to the early onset of age-associated diseases in survivors of pediatric cancers. Read: https://t.co/zPPVfSTLBS h 450 views · 3 likes · 2 reposts · 0 replies Open on X →

Fred Hutch Cancer Center@fredhutch4 Sep

@fredhutch I'd watch coverage and testing speed. Fred Hutch data matters, but a $39,800 daily pill stays theoretical unless labs, payers, and support programs line up. 9 views · 0 likes · 0 reposts · 0 replies Open on X →

Fred Hutch Cancer Center@fredhutch3 Sep

The study provides an enormous amount of training data to inform researchers’ understanding of how a TCR’s chains interact as they seek to design new therapies and predict a TCR’s target using only its gene sequence, Thomas said. 112 views · 1 likes · 0 reposts · 0 replies Open on X →

Fred Hutch Cancer Center@fredhutch3 Sep

Some chains are relaxed enough that about 10% of randomly drawn partners could maintain target specificity, but others are so picky this drops to as low as 0.01%. 24 views · 1 likes · 0 reposts · 1 replies Open on X →

Fred Hutch Cancer Center@fredhutch3 Sep

“That’s a massive spread,” said Thomas, who is the Bezos Family Distinguished Scholar in Viruses and Vaccines. The findings show that scientists will never be able to infer a TCR’s target from only one chain, he said. 26 views · 1 likes · 0 reposts · 1 replies Open on X →

Fred Hutch Cancer Center@fredhutch3 Sep

“We also saw a tuning of recognition,” Minervina said, noting that sometimes a new alpha chain modified specificity instead of destroying it. 107 views · 1 likes · 0 reposts · 1 replies Open on X →

Fred Hutch Cancer Center@fredhutch3 Sep

First author @Asya_Minervina developed a method to systematically assess TCR alpha-beta chain pairing using naturally occurring TCRs. tarting with a TCR of known specificity, she swapped in millions of alpha chains to measure pairing strength and effects on target recognition. ht 80 views · 1 likes · 0 reposts · 1 replies Open on X →

Fred Hutch Cancer Center@fredhutch3 Sep

Sometimes one chain leads, but Minervina found that no chain is a true soloist. The vast majority of the time, while a given beta chain can stably pair with a random alpha chain, it no longer sees the same target: the new TCR is dancing to a different beat. 29 views · 1 likes · 0 reposts · 1 replies Open on X →

Fred Hutch Cancer Center@fredhutch3 Sep

“We know both chains are critical for what the TCR sees,” said @PGTimmune, the senior author on new work in @ScienceMagazine that lays out some of the rules that govern the dance of the TCR chains. “But how much play do we have between the two chains?” https://t.co/YRgsPL5KIE 103 views · 2 likes · 0 reposts · 1 replies Open on X →

Fred Hutch Cancer Center@fredhutch3 Sep

TCR-based therapies against cancer and autoimmune diseases have lots of potential, so it’s important to understand how the two TCR chains work together. 110 views · 1 likes · 0 reposts · 1 replies Open on X →

Fred Hutch Cancer Center@fredhutch3 Sep

T cells fight off infections and cancer using a specialized molecule called the T-cell receptor (TCR). Each new T cell carries a unique TCR made of two molecular chains that pair with a shared goal: Detecting infected or cancerous cells, and eliminating them. 🧵 https://t.co/K9MIG 1.2K views · 17 likes · 6 reposts · 1 replies Open on X →

Fred Hutch Cancer Center@fredhutch3 Sep

“It’s not chemo, and so it becomes a much easier treatment regimen in order to administer and in order to take it is FDA-approved in the second-line metastatic patients, and so it’s a pretty straightforward treatment,” said Fred Hutch's Dr. Sita Kugel. https://t.co/UtBYfoDk3r 975 views · 6 likes · 2 reposts · 1 replies Open on X →

Face aux comptes de taille comparable

14 posts des 90 derniers jours, à côté de la tranche de 10K–100K abonnés. touche moins de monde que ses pairs, mais les engage bien davantage.

Vues médianes108ce compte924médiane pour 10K–100K

Portée, %0.28%ce compte3.62%médiane pour 10K–100K

Engagement, %1.97%ce compte1.52%médiane pour 10K–100K

Indicateur	Ce compte	Médiane pour 10K–100K	Rapport
Vues médianes par post	108	924	0.12×
Portée (vues ÷ abonnés)	0.28%	3.62%	0.08×
Taux d'engagement	1.97%	1.52%	1.29×

Autres comptes de cette tranche → Comparer avec un autre compte → Comment ces repères sont établis →

Growth & engagement

How the posts we collected actually performed: views and reaction rate post by post, what the audience did with them, and where the follower count goes.

Views per post

9753 Sep

1.2K

110

103

107

112

94 Sep

450

359

371

Last 14 collected posts, oldest on the left. The scale is logarithmic: one post can outrun the rest a hundred times over.

Engagement rate per post

0.92%3 Sep

2.07%

1.82%

2.91%

6.90%

2.50%

1.87%

7.69%

8.33%

0.89%

0.00%4 Sep

1.11%

0.28%

2.43%

Reactions — likes, reposts, replies and quotes — divided by views. Median for 10K–100K accounts is 1.52%.

What the audience does

Likes64.2%43 in total

Reposts17.9%12 in total

Replies13.4%9 in total

Bookmarks4.5%3 in total

Share of every reaction we collected for this account. Replies mean argument, reposts mean endorsement, bookmarks mean the post was worth keeping.

The follower curve appears once this account has two daily snapshots — we take one a day, and this one is on its first.

Derniers posts

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Growth & engagement

Views per post

Engagement rate per post

What the audience does

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