Andrew J Sauer MD @AndrewJSauer · 02 Sep 2026
Spironolactone Outcomes RCTs in the Last 20y #TOPCAT (HFpEF) ❓❌ #SPIRITHF (HFpEF) ❓❌ #CLEAR (Post-MI) ❌ #BARACKD (CKD) ❌ #ALCHEMIST (ESKD) ❌ #ACHIEVE (ESKD) ❌ One day we will hopefully have a positive RCT to elevate eminence based medicine to evidence based medicine!
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