David R. Liu @davidrliu · 03 Aug 2026
Today in @NatureBiotech we report the use of phage-assisted evolution (PACE) to reprogram botulinum neurotoxin (BoNT) proteases to trigger cancer cell death. We evolved proteases to cleave procaspase-1 or gasdermin D, inducing cell death and slowing tumor growth in a highly https://t.co/xiaDULwiyH
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