Afshine Emrani MD FACC @afshineemrani · 04 Sep 2026
2/12 GLP-1 drugs do not melt fat.They are keys. The lock is the GLP-1 receptor (GLP-1R) — a G-protein-coupled receptor on cells in:• brainstem and hypothalamus (appetite, “food noise,” reward) • vagus nerve (gut-to-brain fullness signal) • stomach and intestine (slow emptying)
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