Ed Boyden
@eboyden3 · Cambridge, MA · joined 07 Nov 2008
Y. Eva Tan Professor in Neurotechnology, MIT. Mindspan Institute, co-founder, co-CEO. Neuroscientist, inventor, entrepreneur.
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Just published in @natBME: expansion revealing (ExR), a 20x #expansionmicroscopy method that evenly separates proteins from each other for better antibody labeling, and nanoprecise imaging, on ordinary microscopes. Link to PDF: https://t.co/DiOfcDtMa6 https://t.co/JCC6GUndeT
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Temporally multiplexed imaging (TMI) helps ordinary microscopes image many dynamic signals in a living cell. Different signals are associated with fluorophores with different clocklike properties. A movie of a cell is unmixed to see individual signals. https://t.co/TC9Do7bQ8q htt
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Seeing pictures of the GABA receptor, otoferlin, and calmodulin -- taken on an ordinary light microscope using ONE (one nanometer expansion microscopy) -- was thrilling. https://t.co/eplBUBMtGs
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“Expansion microscopy at one nanometer resolution” - so fun to see the shapes of proteins, on an ordinary light microscope!
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The revolution will not be vitrified! Move over #cryoEM & #cryoET, welcome #ONE_Microscopy 😍https://t.co/dxkkqBk1bI Amazing work from @AliHShaib and the Rizzoli lab, building on concepts from @eboyden3 and @HenriquesLab. With a #GABAA receptor teaser from @danielmihaylov7 😉
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@eboyden3 Can you please work with Neuralink? I have been following you for ten years. You are the best. You can fix people. I believe in your work. Follow your heart!
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#Expansionmicroscopy helps see heat shock proteins (Timmerman, Baldwin, and Benesch labs, https://t.co/x2JzzeFNSN), the pathogen Chlamydia trachomatis (Rudel lab, https://t.co/0z9v2SUeDR), and a Drosophila larva (Preibisch lab, https://t.co/IUzExTShrK). From the last paper: https
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