David Sinclair ✓
@davidasinclair · Harvard · joined 10 Mar 2012
Professor researching why we age & how to reverse it. Author & host of Lifespan. Mission: Extend healthy life for all. Views are entirely his own. @joinlifespan
660 064Followers
1 171Following
10 953Posts total
4.3MViews on collected posts
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@davidasinclair It’s recommended for those with high lipoprotein-a by the American college of cardiology
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@davidasinclair Most spring has additives. It’s very hard to find clean aspirin unless you move to willow bark. They all seem to include cancerous additives. Any idea why?
843 views · 0 likes
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Wrote a story about the big asprin debate that missed the point
55.1K views · 147 likes
· 11 reposts · 6 replies
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Is daily aspirin actually bad for you? Lifespan Magazine 📚️ https://t.co/nrDibXIAhu
55.7K views · 18 likes
· 5 reposts · 4 replies
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@davidasinclair There are RCTs showing reduced cognitive performance on statins. RCTs! - not observational studies (what you're pointing to here). There are also specific case reports such as these two: https://t.co/4Z4eohCEWf https://t.co/5FerPXU9tj along with a review of 60 cas
739 views · 20 likes
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@davidasinclair You know, David, I like you
I think you have good intentions and do good work.
But this post shows clearly where your blind spots are
1. This shows spikes and blood sugar to dementia. Everyone in the functional medicine community knows this. In fact, you kno
607 views · 26 likes
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@davidasinclair Are we going to talk about the side effects, too?
I don’t get this statin love…
1.7K views · 21 likes
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Statin use linked to lower risks of all‐dementia, AD, and VaD. No longer a question
181.7K views · 912 likes
· 101 reposts · 89 replies
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Statin use and dementia risk: A systematic review and updated meta-analysis
https://t.co/lBkjSsQop2 https://t.co/gDfL6OhRUR
197.4K views · 124 likes
· 25 reposts · 17 replies
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@davidasinclair I heard there are reports of massive fraud in Japan. The elder dies and the family continues to report them alive to collect pension money.
Not saying there are not many over 100 yrs old.
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@davidasinclair Great, we can live longer to work until 85 before retirement, IF retirement even is a thing then.
Having a healthspan closer to lifespan should be the goal, not just extending the latter.
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@davidasinclair When will we actually receive some of these age reversal treatments you've been going on about for all these years?
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Turning 100 used to make headlines
Now, Japan has 100K centenarians
One day, dying at 100 will feel too young
https://t.co/eUnMRBy9qw
57.6K views · 1.5K likes
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@rajshamani is really a great guy. We sat down to discuss why our hearts, brains & other organs don't age at the same rates, 5 everyday habits linked to 14 years of extra life & which aspects of aging are reversible
Enjoy 💪
https://t.co/5xlO8POmin
38.6K views · 310 likes
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23 years younger epigenetically. Makes sense
84.4K views · 773 likes
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Fasting meets ITOA. New review by Valter Longo et al
https://t.co/UqiK3QOasf https://t.co/4IQQbT2bps
40.9K views · 320 likes
· 40 reposts · 14 replies
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@davidasinclair What about papers that don't replicate? Are there people who self-cite those, too? Or keep talking about the results as if they're rock-solid facts, without explaining to anyone what's going on?
https://t.co/iRk5PSEIYn https://t.co/CqeyeDmmoG
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@davidasinclair Wish I was better at biochem. I'd enjoy working with you. I'm 70, retired, trying to learn FreeCAD. A little propulsion system "I did" design back in the 1970's. 50 years of finessing it in my head, pretty sure it might net me an asteroid if I live long enough.
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In this review, I will not provide any new information but it will keep my publication list growing and earn me citations for research I didn't do.
82.8K views · 359 likes
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Enjoyed a longevity discussion @TIME, a media outlet I've witnessed remain relevant & truthful. So rare these days 🙏
@nkreports @AliceParkNY @TIMEHealth
https://t.co/O7gIQc1U8i
29.6K views · 230 likes
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Longevity medicines might have been available to the world around 2015, if it weren't for a flawed study by a large pharma company that derailed a field & halted trials
15 years later, the lifespan-extending molecules continue to show promise, in this case for kidney disease 🧵 h
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Extending human lifespan is the greatest opportunity of our time https://t.co/zO2yZRYXPl
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Humbled and grateful to be named one of
@techreview Innovators Under 35, and honored to be featured by @antonioregalado. Thank you to the TR35 judges and committee for this recognition. It may help carry me through those inevitable moments of self-doubt when confronting the
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New paper reports that NAD-dependent SIRT1 suppresses retrotransposon RNA, a putative way to slow aging
Cool, but Philipp Oberdoerffer in my lab published this in Cell in 2008 and the authors don’t even mention his work. Uncool
https://t.co/lslV8JagI3
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Everyone’s excited about GLP-1s extending mouse lifespan. Does this mean patients might live longer?
The science explained, what this means for you, plus an interview with lead scientist Dr. Danica Chen📖
https://t.co/VGU9b97zko

52.6K views · 470 likes
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Why do identical twins age at different rates?
In today’s new @Lifespan episode, Drs. Sinclair & LaPlante discuss why we age & what stem cells, mitochondria & exercise teach us about staying healthier for longer 💪
📺 Watch now https://t.co/TZuQmlCp1f https://t.co/hAkymS9zgv h
40.9K views · 66 likes
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Against accounts of the same size
42 posts from the last 90 days, next to the 100K–1M follower range. shown to more people than peers of the same size.
Median views36 365this account5 983median for 100K–1M
Reach, %5.51%this account1.49%median for 100K–1M
Engagement, %0.89%this account0.93%median for 100K–1M
| Metric | This account | Median for 100K–1M | Ratio |
|---|---|---|---|
| Median views per post | 36 365 | 5 983 | 6.08× |
| Reach (views ÷ followers) | 5.51% | 1.49% | 3.70× |
| Engagement rate | 0.89% | 0.93% | 0.96× |
Others in this range → Compare with another account → How these benchmarks are built →
Growth & engagement
How the posts we collected actually performed: views and reaction rate post by post, what the audience did with them, and where the follower count goes.
Views per post
57.6K17 Sep
385
374
268
197.4K18 Sep
181.7K
1.7K
607
739
55.7K
55.1K
843
18819 Sep
201
Last 14 collected posts, oldest on the left. The scale is logarithmic: one post can outrun the rest a hundred times over.
Engagement rate per post
3.02%17 Sep
1.82%
1.87%
3.36%
0.09%18 Sep
0.61%
1.39%
4.61%
2.98%
0.05%
0.30%
0.12%
0.00%19 Sep
0.00%
Reactions — likes, reposts, replies and quotes — divided by views. Median for 100K–1M accounts is 0.93%.
What the audience does
Likes71.3%8 319 in total
Reposts6.6%771 in total
Replies3.4%393 in total
Quotes0.5%57 in total
Bookmarks18.3%2 131 in total
Share of every reaction we collected for this account. Replies mean argument, reposts mean endorsement, bookmarks mean the post was worth keeping.
The follower curve appears once this account has two daily snapshots — we take one a day, and this one is on its first.
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